Metroid Fusion

Metroid Fusion is Samus' first game on the Game Boy Advance and takes place after the happenings of Super Metroid in which she defeats the mother brain for a second time which results in the destruction of Planet Zebes where the space pirates were based.

In Metroid Fusion Samus is infected with a parasitic life form referred to as the "X Parasites" on SR388 which later matures and causes her to loses her special suit which had to be removed. Samus loses all but the most basic of her special abilities and spend the majority of the game investigating the parasite threat in the different areas of space lab which studies life or SR388 infested by the same parasites.

She soon realises that the parasite also has mimicking abilities and that when it infected her suit it copied her abilities when she is at her most powerful and so the "SA-X" (Samus Aran X parasite) was born. Metroid Fusions although a bit linear offers small peaks into the life of Samus and does well to expand the story surrounding Samus her life in the federation and more.

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